Gomez specializes in general orthopaedics and conservative management of hip and knee conditions. Craig Richard Bennett, M. Bennett specializes in general orthopaedics.
See Article History Metabolic bone disease, any of several diseases that cause various abnormalities or deformities of bone. Examples of metabolic bone diseases include osteoporosisricketsosteomalaciaosteogenesis imperfectamarble bone disease osteopetrosisPaget disease of boneand fibrous dysplasia.
In clinical terms, metabolic bone diseases may result in bone pain and loss of height due to compression of vertebraeand they predispose patients to fractures.
The skeletonlike many other tissues of the body, undergoes a constant process of breakdown and renewal. This ongoing process of bone resorption and formation permits the skeleton to adjust to the changes required for healthy functioning Bone disease subtle remodeling to maintain maximal bone strength and to the changes required for healing fractures.
Normal bone provides rigid support and is not brittle. It consists of two major components: Osteoid consists mostly of a fibrous protein called collagenwhile the mineral complexes are made up of crystals of calcium and phosphateknown as hydroxyapatite, that are embedded in the osteoid.
Bone also contains nutritive cells called osteocytes. However, the major metabolic activity in bone is carried out by osteoblastswhich generate the protein matrix, and osteoclastswhich are large multinucleated cells that digest and dissolve the components of bone.
Most metabolic diseases of bone are defined by the extent to which they reduce bone density.
Bone density can be measured in different bones using radiologic techniques. The bones commonly measured are the bones of the lumbar spinehip, and radius a bone in the forearmand the most widely used procedure is dual X-ray absorptiometry.
Bone density peaks at about the age of 30 and varies according to sex and genetic background. For example, bone density is higher in men than in women and is higher in African Americans than in Europeans or Asians.
The result is a measurement known as the T score. The results of measurements of bone density can also be expressed as Z scores. A Z score of 0 is the mean bone density of people of the same age, sex, and genetic background.
Low T or Z scores are associated with an increased risk of bone fracture.Abstract. Bone disease is observed in almost 80% of newly diagnosed symptomatic multiple myeloma patients, and spine is the bone site that is more frequently affected by myeloma-induced osteoporosis, osteolyses, or compression fractures.
Paget's disease of bone interferes with your body's normal recycling process, in which new bone tissue gradually replaces old bone tissue. Over time, the disease can cause affected bones to become fragile and misshapen.
Paget's disease of bone most commonly occurs in the pelvis, skull, spine and. Renal osteodystrophy is currently defined as an alteration of bone morphology in patients with chronic kidney disease (CKD).
It is one measure of the skeletal component of the systemic disorder of chronic kidney disease-mineral and bone disorder (CKD-MBD).
Oral Health and Bone Disease Osteoporosis is a condition in which the bones become less dense and more likely to fracture. This disease can affect any bone in the body, although the bones in the hip, spine, and wrist are affected most often. Bone disease, any of the diseases or injuries that affect human bones.
Diseases and injuries of bones are major causes of abnormalities of the human skeletal system. Although physical injury, causing fracture, dominates over disease, fracture is but one of several common causes of bone disease, and disease is in fact a common cause of fracture.
Paget Disease of Bone Paget disease of bone (PDB) is the second most common bone remodeling disease after osteoporosis. PDB affects approximately 1 to 2 percent of white adults aged 55 or older, according to an April review article published in " Therapeutic Advances in Musculoskeletal Disease."Founded: Jun 17,